• The fact that KNDy neurons activity is sensitive for circula

  2022-06-13

  

  The fact that KNDy neurons activity is sensitive for circulating hormones related with control of Chaetocin homeostasis was demonstrated in other studies (Cejudo Roman et al., 2012; Navarro et al., 2011). It is well documented that leptin plays an important role in the regulation of the gonadotroph

• br Results br Discussion br Materials and Methods br Introdu

  2022-06-13

  

  Results Discussion Materials and Methods Introduction Deoxyribonucleic CGRP (rat) mg (DNA) is among the most important biopolymers in living organisms alongside carbohydrates and proteins. DNA is a linear polymer consisting of four types of nucleobases, deoxyribose, and phosphate. The b

• br Introduction Glycoproteins represent a staggeringly small

  2022-06-13

  

  Introduction Glycoproteins represent a staggeringly small fraction of proteins analyzed by high-resolution techniques despite high concentrations at the cell surface and critical roles in many human diseases. Though one-half or more of all human proteins are predicted to contain a carbohydrate ch

• br Introduction Given the growing acceptance of ergothionein

  2022-06-13

  

  Introduction Given the growing acceptance of ergothioneine (ET) as a biologically important agent with potential therapeutic applications [[1], [2], [3], [4]] it is increasingly important to clearly establish the role of the organic cation transporter (novel) type 1 (OCTN1). OCTN1 was discovered

• Hypocotyl development is a crucial phase of

  2022-06-10

  

  Hypocotyl development is a crucial phase of early vegetative growth that influences seedling vigor contributing to fitness and productivity of a plant system (Stinchcombe and Schmitt, 2006; Luo et al., 2017). The development of a hypocotyl is characterized by an initial slow growth phase followed by

• br Summary br Conflict of

  2022-06-10

  

  Summary Conflict of interest Acknowledgments This study was supported by Grant No. 2014/13/B/NZ7/02277 from the National Science Centre, Poland. Introduction Progesterone (P) is an anticonvulsant hormone (Backstrom et al., 1984, Herzog, 1995, Herzog, 1999, Frye et al., 2000, Reddy, 2002

• br G protein coupled receptor GPR also

  2022-06-10

  

  G-protein coupled receptor 40 (GPR40), also known as a free fatty health-related receptor, is dominantly expressed in pancreatic β cells and intestine K, L cells., . Besides, GPR40 is also reported to be expressed in brain, but its function is still unknown. It is well documented that GPR40 agonis

• A general synthesis of the tetrazole is shown

  2022-06-10

  

  A general synthesis of the tetrazole is shown in . First, a magnesium-halogen exchange reaction quenched with DMF afforded benzo[]thiophene-5-carbaldehyde , which was further decorated with a bromine at the 3-position (). A Suzuki reaction with -tolylboronic Riboflavin followed by reduction of the

• It raises a question about origin

  2022-06-10

  

  It raises a question about origin of the sensitivity to Ca of both FBPase isozymes. Was the ancestral vertebrate FBPase inhibited by calcium similarly to the liver isozyme? And is the high sensitivity of FBP2 a new evolutionary feature of warm-blooded vertebrates? Additionally, since subcellular lo

• br Introduction Fructose bisphosphatase FBPase EC catalyses

  2022-06-10

  

  Introduction Fructose 1,6-bisphosphatase (FBPase; EC 3.1.3.11) catalyses the irreversible reaction of hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate [1]. Genetic and kinetic studies so far have demonstrated that at least two distinct isoenzymes of FBPase e

• Therefore the histomorphology and the comprehensive analysis

  2022-06-10

  

  Therefore, the histomorphology and the comprehensive analysis of TMJ-RA pathogenesis need to be completed although clinical findings in TMJ-RA are similar to RA in other joints [41]. Especially for the dentist, the difficulties associated with diagnosing TMJ-RA patients [49] posing challenges to dia

• In summary we have discovered

  2022-06-10

  

  In summary, we have discovered the first examples of movement of Asp189 upon binding to fXa inhibitors. A series of novel and potent fXa inhibitors with a phenyltriazolinone P moiety were identified. Although the general binding mode compared to our previously-reported fXa inhibitors was maintained,

• br Materials and methods br Results and discussion br

  2022-06-10

  

  Materials and methods Results and discussion Conclusion The as-designed system was based on the assembly of MSN-Cy and TPGS, which was dominated by π-π stacking interactions. By the strong mutual force, Cypate and TPGS formed a compact layer around the MSN core, which blocked the drug leaka

• In a preliminary communication we showed that AT

  2022-06-10

  

  In a preliminary communication, we showed that AT and ETB receptors colocalize and coimmunoprecipitate in renal proximal tubule cells, and stimulation of the AT receptor increases ETB receptor expression in Wistar-Kyoto (WKY) rats [abstract; Zeng C,, 26:80A, 2003]. We hypothesize that the ETB recept

• Zanamivir br Memories can last a lifetime long after the

  2022-06-10

  

  Memories can last a lifetime, long after the transient events have passed. The fact that information stored in the Zanamivir can outlast the environmental trigger implies that enduring cellular changes in the central nervous system underlie memory. Epigenetic modifications of DNA and chromatin st

15868 records 409/1058 page Previous Next First page 上5页 406407408409410 下5页 Last page