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CLL associated HLH was first documented in the
2019-04-18
CLL associated HLH was first documented in the form of a case series report which included six patients treated for CLL who subsequently developed the phagocytic syndrome months to years later.[7] As these cases occurred prior to publication of the 1991 HLH diagnostic guidelines, the authors postula
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Introduction Leukaemias lymphomas and multiple
2019-04-18
Introduction Leukaemias, lymphomas and multiple myeloma can be the dreadful sequelae of viral infections. RNA oncogenic viruses, which are also known as retroviruses, were initially known to cause lymphoproliferative disorders only in animals, but have also been reported to demonstrate their transf
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The results described thus far suggest that PtAF induced
2019-04-18
The results described thus far suggest that PtAF-induced atrial remodeling combined with acute atrial stretch facilitates anchoring of 3-D scroll waves to the border of atrial pectinate muscle and prolongs their life span in favor of AF maintenance. However, why is it that scroll waves anchor to the
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In order to treat metastatic
2019-04-18
In order to treat metastatic bone disease effectively all steps involved in the metastatic cascade need to be taken into account as for example the interactions between primary and secondary sites, tumour cell–bone cell cross talk and osteomimicri [8]. Therefore, concomitant targeting of both the tu
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br Discussion False tendons are
2019-04-18
Discussion False tendons are usually benign, intraventricular myocardial structures, which may cause a musical murmur [1], rate-dependent ventricular extrasystoles, functional mitral regurgitation, or deformation of the LV cavity due to mechanical stretch and dilatation of the LV wall [1,2]. Fals
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Concurrent with the clinical evaluation
2019-04-18
Concurrent with the clinical evaluation of the family, the genetic findings from a molecular autopsy may help to elucidate the cause of death in the decedent, as well as provide a basis for cascade genetic testing of at-risk family members. Offering cascade genetic testing to asymptomatic relatives
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El segundo estudio lo presenta
2019-04-18
El segundo estudio lo presenta Diana Sofía Sánchez, quien aborda de Rosa Beltrán. Texto en el que nos convida de su propuesta basada en: 1 la representación de la familia relacionada con su búsqueda de normalidad, y 2º la reconstrucción puntual de los fracasos y absurdos de la política mexicana. La
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Los tres aspectos se alados del marco
2019-04-18
Los tres aspectos señalados del marco paratextual se encuentran ligados d-biotin las condiciones de producción y de publicación de la novela y allanan el camino de la apropiación y de la subversión textual que realizan sus traductores criollos tras la máscara de la fraternidad de los desterrados. Es
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In the past decade preclinical studies have addressed the
2019-04-18
In the past decade, preclinical studies have addressed the putative role of non-coding RNAs in tumorigenesis, metastasis and therapy response in osteotropic cancers. Besides long non-coding RNAs, microRNAs (miRs) represent a class of small non-coding RNAs, (18–25 nucleotides long), that regulate pro
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It means an opportunity As we concern ourselves with
2019-04-18
It means an opportunity. As we concern ourselves with the prominence of health in the new agenda, it\'s easy to forget that (human) development is by definition people-centred, and that living a long, healthy, and creative life is its cornerstone. The expansion of the new goals to encompass many (if
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Ulises criollo pertenecer a a lo que en ingl
2019-04-18
Ulises criollo pertenecería dihydrofolate reductase inhibitor lo que en inglés se cataloga como nonfiction prose. Al escribirlo la principal intención de Vasconcelos no fue la de narrar en el sentido ficcional (imaginativo, desinteresado, novelesco) sino interpretar, sentar una comprensión de su épo
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We present a case report of a patient with chronic
2019-04-18
We present a case report of a patient with chronic myeloid leukemia (CML) who developed bilateral renal artery stenosis during tyrosine kinase inhibitor (TKI) therapy. Only a few reports associate TKIs with acute renal failure, and renovascular hypertension has not been previously described. Reports
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Romiplostim is an Fc fusion protein
2019-04-18
Romiplostim is an Fc-fusion protein that augments thrombopoiesis by binding to and activating the thrombopoietin receptor. It is approved for the treatment of thrombocytopenia in patients with chronic immune thrombocytopenic purpura who have had an insufficient response to corticosteroids, immunoglo
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Wortmannin Introduction Tumor metastases of the skeleton
2019-04-17
Introduction Tumor metastases of the skeleton occur in up to 80% of patients in progressed stages of cancer, most commonly in cases of breast, lung, prostate, kydney and thyroid tumors [1,2]. Bone metastases are often associated with pathologic fractures, hypercalcemia and spinal cord compression,
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Senexin B Supplier br Conclusion br Conflict of
2019-04-17
Conclusion Conflict of interest This work was supported by Medtronic Japan. MN received honoraria from Medtronic Japan, St. Jude Medical Japan and Boston Scientific Japan. YE and TI received honoraria from Medtronic Japan. HS received honoraria from Japan Lifeline. YA, TT, and KK are employees
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