• Repurposing use of approved drugs for

  2019-05-16

  

  Repurposing (use of approved drugs for new indications) or repositioning (use of drugs whose development was not continued for new indications) of existing drugs has been put forward as a method to overcome some of these issues. Indeed, drug repositioning and repurposing could lead to higher rates o

• Interpretation Stakeholders from sectors not historically en

  2019-05-16

  

  Interpretation Stakeholders from sectors not historically engaged in health care are forming unique partnerships with common goals and a willingness to address the challenge of global cancer care. Funding None. Declaration of interests Abstract Background Since 2013 medical students from North

• The Zika virus epidemic is spreading countries

  2019-05-16

  

  The Zika virus epidemic is spreading: 63 countries are now reporting transmission, over 1500 cases of related microcephaly or CNS malformations have been confirmed this year, and knowledge on the disease is advancing slowly. Adding to the tension around Zika, at the epicentre of the outbreak, Brazil

• Consequently in asymptomatic individuals multiple and

  2019-05-16

  

  Consequently, in asymptomatic individuals, multiple and repeated ECG recordings rather than drug testing are recommended for detecting the transient appearance of a spontaneous type 1 ECG, which may indicate the future development of arrhythmic events. Moreover, in addition recording at higher lead

• br Erythropoietin and the HSC

  2019-05-16

  

  Erythropoietin and the HSC niche Many molecules produced both locally and systemically, including erythropoietin (Epo) and adrenergic catecholamines, also appear to affect HSC niche and metastatic lesions in the bone marrow. EPO is a hematopoietic hormone produced predominantly in the kidneys in

• In this study all tumors were Campanacci stage

  2019-05-16

  

  In this study, all tumors were Campanacci stage 3, which is a significantly higher proportion than in our database [9]. Such a high stage usually suggests that a tumor is highly aggressive and may be a high-risk factor for lung metastasis. Previous reports have also suggested that the stage of a GCT

• On the other hand it has been reported that

  2019-05-16

  

  On the other hand, it has been reported that the Purkinje network can survive in patients with ischemic or idiopathic cardiomyopathy [6], and in patients with T0901317 failure and left bundle branch block (LBBB). In addition, idiopathic LV tachycardia that involves the Purkinje network as the circui

• br Conflicts of interest br

  2019-05-16

  

  Conflicts of interest Acknowledgment This work was supported, in part, by a grant from the Experimental Research Center ELPEN (Y97/2-12-2013). The funding source had no involvement in the study design, in the collection, analysis and interpretation of data, in the writing of the report, and in

• Tobacco use is poised to kill as many as

  2019-05-16

  

  Tobacco use is poised to kill as many as 1 billion people in the 21st century, primarily from non-communicable diseases. Less often noted is the effect of tobacco use and second-hand smoke exposure on maternal and child health. Cigarette smoking during pregnancy poses serious risk to the mother and

• Heat shock facilitates the folding of various

  2019-05-15

  

  Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is

• br INTRODUCCI N br Qu hacer

  2019-05-15

  

  INTRODUCCIÓN ¿Qué hacer con las derrotas políticas? ¿Qué hacer frente 2b3a inhibitors ellas? ¿Cómo procesarlas y transfigurarlas en una escuela de conocimiento? Sin duda, estos interrogantes recorren como un fantasma toda tradición de pensamiento y transformación que se precie de ser crítica. C

• Sin embargo las identidades sexuales politizadas no han sido

  2019-05-15

  

  Sin embargo, las identidades sexuales politizadas no han sido simples corolarios de la homofobia y trato despectivo hacia las sexualidades contra culturales. Para hacerse visibles, requirieron complejas condiciones sociales y políticas con el fin de producir un sentido de experiencia de comunidad qu

• br Results In all patients no abnormalities were found

  2019-05-15

  

  Results In all patients, no abnormalities were found in the left axillary, left subclavian, or left brachiocephalic veins, such as blood vessel occlusion or stenosis. The procedure time was 138.6±41.8min in the conventional puncture group (Group A) and was 109.8±23.2min in the catheter-guided pun

• Discussion Mantle cell lymphoma is

  2019-05-15

  

  Discussion Mantle cell lymphoma is a distinct type of mature B-cell neoplasm that accounts for approximately 3–10% of non-Hodgkin\'s lymphoma. It is referred to several aliases, such as lymphocytic lymphoma of intermediate differentiation, mantle zone lymphoma, centrocytic lymphoma. Diffusion of no

• En los ltimos a os se han multiplicado

  2019-05-14

  

  En los últimos años se han multiplicado los procesos de resistencia Cyclopamine cost proyectos mineros, de represas y de infraestructura que despojan de tierras o que tienen impactos ambientales severos. El surgimiento de nuevas coordinaciones intercomunitarias, como la Alianza Territorial Mapuche y

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