• MSCs can express several WNT ligands Cho et al

  2018-11-02

  

  MSCs can express several WNT ligands (Cho et al., 2006; Etheridge et al., 2004). This endogenous WNT signaling may play a negligible role in MSC expansion, because we found no significant effects on cell proliferation or subsequent differentiation when endogenous WNT proteins were prevented. However

• Cell cycle adaptations in human ESCs hESCs are

  2018-11-02

  

  Cell-cycle adaptations in human ESCs (hESCs) are less defined. In contrast to mESCs, hESCs exhibit significant fluctuation of cyclin expression in a cell-cycle-dependent manner (Neganova et al., 2009), indicating differences in the regulation of key cell-cycle proteins between the two cell types. Si

• neurokinin 1 receptor Regardless of the detailed mechanisms

  2018-11-02

  

  Regardless of the detailed mechanisms of metabolic regulation in ESCs, recent studies indicate that reprogramming MEFs into iPSCs involves dramatic changes in cell metabolism from oxidative phosphorylation to glycolysis (Folmes et al., 2011). Somewhat paradoxically, however, the early phase of the m

• Flow cytometry can assess cell surface expression

  2018-11-02

  

  Flow cytometry can assess cell-surface expression of pluripotent markers (e.g., TRA-1-60, TRA-1-81) at the single-cell level and is easily scalable using fluorescent cell barcoding (FCB) (Krutzik and Nolan, 2006). In FCB, each sample in each well is labeled with a different signature, or barcode, of

• imidazoline br Experimental Procedures br Author Contributio

  2018-11-02

  

  Experimental Procedures Author Contributions Acknowledgments We thank A. Villanueva, C. Saura, C. Cruz, A. Fernández, E. Nadal, M. Martin, and R. Iggo for reagents and helpful advice, A. Welm and Y. DeRose for sharing PDX models, V. Peg, X. Serres, J. Balmaña, J. Pérez, and C. Hierro for pr

• Scanners with LIDE LED indirect exposure are an

  2018-11-02

  

  Scanners with LIDE (LED indirect exposure) are an improved version of the CIS technology. Here the light source uses powerful tri-color RGB (Red, Green, Blue) LEDs, and the radiation is directed to the object via quartz fibers ensuring uniform exposure over the entire width of the original scanner w

• br Conclusion The Hartree Fock approach was used for

  2018-11-02

  

  Conclusion The Hartree–Fock approach was used for finding wave functions and single-electron energies of the sodium trk receptor in the ground and the excited states. The photoionization amplitudes and the photoabsorption cross-sections for this atom were computed through RPAE which explains the

• br Then it is easy to calculate and

  2018-11-02

  

  Then, it is easy to calculate and and from (3) the value of ∆l∑(T). As it follows from the analysis of the response of a polymeric crystal to mechanical and thermal treatment, two types of deformation appear in chain molecules being the stretching of structural elements and the change of these

• br x and x are the input and output diaphragm

  2018-11-02

  

  Δx1 and Δx2 are the input and output abscisic acid widths respectively; ξ is the measure of the aberration blurring of the input diaphragm image in the vicinity of the output diaphragm. Let both diaphragms be at zero potential (see Fig. 1a), and the emitter under investigation be at the potentia

• Our analyses also show that those born to

  2018-11-02

  

  Our analyses also show that those born to young and older mothers are more likely to smoke, and to consume alcohol regularly, while those born to older mothers are less likely to exercise regularly, even after adjusting for parental SES, socio-demographic characteristics, and self-reported depressio

• br Las v lvulas de escape la informalidad y la

  2018-11-01

  

  Las válvulas de escape: la informalidad y la emigración laboral La emigración laboral, que se había intensificado en el segundo decenio de los noventa ante la caída del empleo en el campo, se vio notoriamente frenada a partir del 2000, a raíz tanto de las recesiones en Estados Unidos, como de nue

• br New Compounds Specifically Developed to Target Ageing br

  2018-11-01

  

  New Compounds Specifically Developed to Target Ageing Biomarkers for Detecting Drug Efficacy Against Ageing To accurately assess the impact of possible therapeutics on human ageing, suitable biomarkers that correlate with, and are likely causative of, increased physiological age are needed. A

• To address these barriers interventions are needed that impa

  2018-11-01

  

  To address these barriers, interventions are needed that impact macro-level structural factors, such as reducing poverty and income inequality, increasing educational attainment, and fostering more equitable gender norms. As seen by the Tucker et al. review, social determinants of health matter, and

• br Data experimental design materials

  2018-11-01

  

  Data, experimental design, materials and methods Specifications table Value of the data Data Mean peak values obtained from intact clemastine fumarate Supplier (IC), detergent-soluble extracts (SD) and detergent-insoluble extracts (ID) associated with immature (IC2, SD2, ID2) and mature

• Following Eqs the basic version of the multiplicative error

  2018-11-01

  

  Following Eqs. (1–4), the basic version of the multiplicative error model (MEM) has been developed to upgrade the GARCH ( to include the effects of the volatility of other markets in each equation of volatility as follows: Within this context, we estimate several models that include the dummy varia

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