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To determine if the overexpression of miR
2018-11-09
To determine if the overexpression of miR-137 negatively regulate EFNB2 expression, human neuroblastoma SH-SY5Y cells were transfected with mature miR-137 sequences or negative control miRNAs. The results showed that the overexpression of miR-137 did not affect the mRNA expression of EFNB2 but signi
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sirtuin activators The vast majority of malaria infections i
2018-11-09
The vast majority of malaria infections in low endemic settings are of low density (Imwong et al., 2016) but can contribute considerably to onward malaria transmission (Slater et al., 2015). However, the impact of current ACT and ACT-PQ on preventing onward malaria transmission from these low-densit
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ELA causes children to experience their environment as
2018-11-09
ELA causes children to experience their environment as threatening, perceiving themselves as having no value and regarding the future as being not trustworthy (Dube et al., 2003). A history of ELA consequentially increases the risk of developing a psychiatric disorder in adulthood (Rojo-Moreno et al
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Second individuals with ADHD compared to controls
2018-11-09
Second, individuals with ADHD, compared to controls, attenuated VLFO power to a lesser degree when working relative to resting but the spatial distribution of REST-to-WORK attenuation was similar between the two groups. The ADHD group also displayed a significantly elevated error rate during the per
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In early and mid adolescence peer relationships
2018-11-09
In early- and mid-adolescence, peer relationships are particularly salient: individuals show an increased sensitivity to acceptance and rejection by peers (Brown, 2004; Nelson et al., 2005; Sebastian et al., 2010a), and an increase in awareness of others’ opinions (Parker et al., 2006; Vartanian, 20
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To assess the hypothesis neuronal elements presumably affect
2018-11-09
To assess the hypothesis, neuronal elements presumably affecting early daily habits and successful life are reviewed. As such neuronal elements, 5-HT, oxytocin, the PFC and the ventral/dorsal striatum were selected with reference to previous studies [9]. Relationships among these elements are shown
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En el Cuadro se muestran los
2018-11-09
En el Cuadro 3, se muestran los resultados de la prueba de causalidad de Granger, pero usando ahora el gasto presupuestal en lugar de tan sólo el gasto presupuestal primario, que como se ha comentado la diferencia entre ambos es el costo financiero de la operación del Estado, el pago de intereses.
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Estimados Lectores En sus manos tienen el n mero
2018-11-09
Estimados Lectores: En sus manos tienen el número 400 de Economía Informa, lo cual representa un motivo de orgullo y festejo para nuestra comunidad; especialmente para quienes han hecho posible su existencia y su publicación periódica durante todos estos años; me refiero no solo ARQ 621 los profeso
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br Evoluci n de la oferta
2018-11-09
Evolución de la oferta del mercado de minoristas en México La gráfica 2 muestra cómo el desempeño de la oferta de las minoristas (aproximada por la superficie de ventas) sigue muy de cerca el desempeño del pib de la economía nacional. También se puede interpretar como que la estrategia de oferta
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The tight regulation of its dosage and allelic expression
2018-11-09
The tight regulation of its dosage and allelic expression led us hypothesize that Igf2 has a very precise function in stem cells: early in development, Igf2 would ensure the adequate expansion of stem H-Lys(Ac)-OH.HCl Supplier present in developing organs, then during post-natal life, Igf2 would c
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The most well studied angiogenic factor that is regulated
2018-11-08
The most well-studied angiogenic factor that is regulated by hypoxia is VEGF; hypoxic induction of an HIF-1-dependent bFGF autocrine loop drives angiogenesis, over-expression of Ang-1 causes a significant increase in HIF-1 stabilization and PDGF-BB participates in an autocrine-paracrine survival pat
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The Rad protein is a key
2018-11-08
The Rad51 protein is a key player in DNA double-strand break (DSB) repair by homologous recombination (HR). The expression level of Rad51 typically varies throughout the cell cycle, with the lowest expression found in the G1 phase, increasing throughout S-phase, and peaking in G2/M (Chen et al., 199
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Main Text One promise of IPSC
2018-11-08
Main Text One promise of IPSC-based cell therapy is that personalized medicine using cells from the patient may be feasible. Somatic cells could be harvested and reprogrammed with integration-free methods to produce a stock of clinically compliant pluripotent cells ready for use at any time in late
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A number of reports have
2018-11-08
A number of reports have demonstrated that pluripotent ESCs can form embryoid bodies (EBs) and spontaneously differentiate into PGCs and haploid spermatids in vitro (Geijsen et al., 2004; Hayashi et al., 2011; Kee et al., 2009; Toyooka et al., 2003), thereby providing an alternative model to investi
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Whereas continuous exposure to all three factors resulted in
2018-11-08
Whereas continuous exposure to all three factors (4+) resulted in higher levels of DE genes, there was no significant difference in the proportion of Foxa2+Sox17+ dhpg when compared to transient Wnt activation (2+2−). Surprisingly, T expression in a fraction of differentiated cells was detected in
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