• Baseline WBC count and baseline measures of hepatic and

  2019-04-19

  

  Baseline WBC count and baseline measures of hepatic and renal function for responders and nonresponders are shown in Table 1. No relationship was evident between responders to decitabine or treatment choice and baseline WBC counts, or between responders and baseline measures of hepatic function (ALT

• Chronic myelogenous leukemia blast crisis is highly refracto

  2019-04-19

  

  Chronic myelogenous leukemia blast crisis is highly refractory to standard induction chemotherapy, with a response rate of less than 20–30% [12,13]. In patient\'s with Imatinib resistant disease Dastanib and Nilotinib can help achieve hematological response however neither drug has been reported to

• The number of residents in London who were originally

  2019-04-19

  

  The number of residents in London who were originally from the 21 endemic countries in Central and South America was calculated from the 2011 UK National Census and was stratified by borough. We did not include undocumented migrants and individuals born to mothers from endemic Latin American countri

• The concept of metronomic chemotherapy

  2019-04-19

  

  The concept of metronomic chemotherapy began in the 1990s, when Kerbel showed chemotherapeutic agents may be able to target tumor vessel endothelial cells. In 2000, Browder et al demonstrated a more frequent, lower dose of cyclophosphamide, i.e. anti-angiogenic schedule, could induce response in tum

• The beats with high amplitude J wave

  2019-04-19

  

  The beats with high-amplitude J wave with short preceding DIs induced low systolic blood pressure, indicating weak cardiac contractility due to decreased calcium influx through I and calcium release during ventricular systole. In contrast, the beats with low-amplitude J wave preceded by long DIs ind

• The requirements for establishing this arrhythmia are as

  2019-04-19

  

  The requirements for establishing this arrhythmia are as follows: (1) a slow pathway (or maybe a fast pathway) should not have retrograde conduction; and (2) the refractory buy SL-327 of the distal common pathway must be shorter than the difference in the conduction times over the fast and slow pat

• br Conclusions Wavelet algorithm is an effective tool

  2019-04-19

  

  Conclusions Wavelet algorithm is an effective tool for the discrimination of tachycardia. However, it is affected by myopotential interference, which can lead to inappropriate detections. Thus, we should keep this drawback in mind when results reveal a Can-RV coil EGM amplitude of less than 5mV.

• br The west African outbreak of Ebola virus

  2019-04-19

  

  The 2014–15 west African outbreak of Ebola virus disease is unprecedented in scale, especially in Sierra Leone, which as of May 15, 2015, had reported 8598 confirmed cases and 3538 confirmed Ebola-related deaths. Sierra Leone\'s response to this emergency has been compromised by a fragile health s

• Se temos ent o um passado

  2019-04-18

  

  Se temos, então, um passado dilution calculation comum e uma gente que “sobreviveu a séculos de genocídio”, parece ser a língua portuguesa e as trocas comerciais direcionadas para os Estados Unidos e para a Europa que nos isolam, como se disséssemos: “Não trabalhamos com pobres como nós”, “Apesar d

• CLL associated HLH was first documented in the

  2019-04-18

  

  CLL associated HLH was first documented in the form of a case series report which included six patients treated for CLL who subsequently developed the phagocytic syndrome months to years later.[7] As these cases occurred prior to publication of the 1991 HLH diagnostic guidelines, the authors postula

• Introduction Leukaemias lymphomas and multiple

  2019-04-18

  

  Introduction Leukaemias, lymphomas and multiple myeloma can be the dreadful sequelae of viral infections. RNA oncogenic viruses, which are also known as retroviruses, were initially known to cause lymphoproliferative disorders only in animals, but have also been reported to demonstrate their transf

• The results described thus far suggest that PtAF induced

  2019-04-18

  

  The results described thus far suggest that PtAF-induced atrial remodeling combined with acute atrial stretch facilitates anchoring of 3-D scroll waves to the border of atrial pectinate muscle and prolongs their life span in favor of AF maintenance. However, why is it that scroll waves anchor to the

• In order to treat metastatic

  2019-04-18

  

  In order to treat metastatic bone disease effectively all steps involved in the metastatic cascade need to be taken into account as for example the interactions between primary and secondary sites, tumour cell–bone cell cross talk and osteomimicri [8]. Therefore, concomitant targeting of both the tu

• br Discussion False tendons are

  2019-04-18

  

  Discussion False tendons are usually benign, intraventricular myocardial structures, which may cause a musical murmur [1], rate-dependent ventricular extrasystoles, functional mitral regurgitation, or deformation of the LV cavity due to mechanical stretch and dilatation of the LV wall [1,2]. Fals

• Concurrent with the clinical evaluation

  2019-04-18

  

  Concurrent with the clinical evaluation of the family, the genetic findings from a molecular autopsy may help to elucidate the cause of death in the decedent, as well as provide a basis for cascade genetic testing of at-risk family members. Offering cascade genetic testing to asymptomatic relatives

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