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Gefitinib The blocking agents tested here were mercaptoundec
2018-10-30
The blocking agents tested here were mercaptoundecanol (MCU), polyethylene glycol (PEG, 1kDa or 5kDa), bovine serum albumin (BSA), and chicken serum albumin (CSA). The surfactant Tween 20 was used in combination with some of the mentioned blocking agents. MCU is a hydroxyl-terminated long-chain alka
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Obtaining accurate concentrations of certain peptides
2018-10-30
Obtaining accurate concentrations of certain peptides is difficult, but reliable structural content calculations can be performed without knowing the exact concentrations of peptide by g-factor analysis [15]. The dimensionless g-factor is independent of path length, concentration, amino acid content
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El escepticismo se gest a lo
2018-10-30
El escepticismo se gestó availability lo largo de los últimos 15 años del siglo pasado, cuando debido a la crisis del petróleo y la deuda externa se llevó a cabo la primera generación de reformas, todas de tipo macroeconómico: estabilización, finanzas públicas, privatización de empresas paraestatale
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br Un an lisis de los
2018-10-30
Un análisis de los hechos estilizados En España, las políticas económicas y la entrada en la Unión Europea parecían obtener resultados favorables. La tasa de inflación media anual en los primeros diez años de política monetaria única (1999-2008) fue de 2.1%, alrededor del objetivo fijado por el b
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La empresa moderna independientemente de su
2018-10-30
La empresa moderna, independientemente de su tamaño, puede verse como la unidad básica de la economía, ya que es un importante centro en donde se toman decisiones clave. Dentro del conjunto de decisiones relevantes que la empresa debe tomar se incluyen no solo cuánto producir o cuál precio determin
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El an lisis de la
2018-10-30
El análisis de la austeridad desde una perspectiva histórica permite evaluar la orientación cíclica de la política fiscal. De aquí surgen preguntas de investigación adicionales tales como la posible relación causal entre austeridad, por un lado, y ciclos y tendencias económicas, por el otro. Por eje
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Based upon the proposals of Bai a
2018-10-30
Based upon the proposals of Bai (1997a,b) and Bai and Perron (1998), it is aim to investigate whether the accumulation of public debt implies more restrictive policies by the Brazilian government. In the Barro\'s (1979) model, also applied by Rocha (1997) and Luporini (2000), the sustainability cond
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Introduction Remittances are a new financial phenomena and o
2018-10-30
Introduction Remittances are a new financial phenomena and one of the main important sources of incomes based on it seize and economic impact in the world. Data from (World Bank, 2014) indicates that global remittance is $430 billion dollar in 2011 and remittance is 0.31% of global GDP in 2009. The
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ICl with aberrant features are not observed
2018-10-30
ICl with aberrant features are not observed in and mice. Rather, comparison of the reduction in [peak ICl]max and gClmax observed in and mice with the semi-quantitative immunohistochemical analysis of Clc-1 in these animals support the hypothesis that the decrease in ICl in these two strains may be
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br The article by Ghosh and
2018-10-30
The article by Ghosh and Ghealen in the current issue of EBioMedicine provides new insights into the pathophysiology of the inflammatory system in Alzheimer\'s disease (AD). The story describing the accumulation of aggregated proteins in the AD brain, including β-amyloid and tau protein, has been
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In keeping with a previous report in out
2018-10-30
In keeping with a previous report in 842 out-patients with stable cardiovascular disease (Parker et al., 2009), t-ucMGP correlated positively with eGFR. t-ucMGP, in the literature often referred to as ucMGP, predominantly consists of phosphorylated MGP and at variance with dp-ucMGP is not a biomarke
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Understanding how barrier tissues function is essential for
2018-10-30
Understanding how barrier tissues function is essential for the design of effective pharmaceutical compounds. Once these devices are transitioned from research to clinical use, and we have more accurate predictive models early on in the development process, we will likely see an end to the recent st
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AG-014699 Sepsis is a serious concern and
2018-10-30
Sepsis is a serious concern and yet the emerging exciting frontiers in biomedicine such as the study by Bauer et al. (2016) multi-omics (Özdemir et al., 2015b; Higdon et al., 2015; Özdemir and Kolker, 2016) and metagenomics technologies (Birko et al., 2015) and innovation foresight (Özdemir et al.,
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Treatment of recipients with the pro inflammatory PAMP poly
2018-10-30
Treatment of recipients with the pro-inflammatory PAMP, poly(I:C), prior to fresh HOD RBC transfusion resulted in alloantibody production comparable to the response to stored RBCs (Fig. 1e). It should be noted that this study did not directly address whether the demonstrated pro-inflammatory cytokin
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In a historic referendum on June the UK voted to
2018-10-30
In a historic referendum on June 23, 2016, the UK voted to leave the European Union (EU) after more than four decades of membership. For the time being, the UK is still a member of the EU until the UK government triggers Article 50 of the Lisbon Treaty–which probably won\'t happen before the end of
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