• The association between neighborhood poverty neighborhood ra

  2018-11-05

  

  The association between neighborhood poverty, neighborhood racial composition and pregnancy-related weight may be related to obesogenic neighborhoods plagued with unhealthy food environments, built environments that discourage physical activity, high crime, and widespread psychosocial stressors (Cul

• The second hypothesis relates to infants

  2018-11-05

  

  The second KN-93 hydrochloride relates to infants’ iron stores at birth, which form infants’ primary source of iron for the first months of life. Iron status of mothers during pregnancy is a key determinant of infant iron stores at birth (Allen, 2000). In our ENSIN sample we find that infants (6–12

• The fact that social capital was higher among not only

  2018-11-05

  

  The fact that social capital was higher among not only dog owners may have a number of alternative explanations that merit further exploration. One glutamate receptor antagonist is that pets (of any kind) may be linked to perceptions of trust, a central tenant of social capital. Some observational s

• GW5074 We found little consistency in how adolescent

  2018-11-05

  

  We found little consistency in how adolescent neighbourhood social environments have been both conceptualised and operationalised. When operationalised the various concepts of adolescent neighbourhood measures were largely indistinct. Again, this is similar to findings from the previous review by Sa

• The discount rate is the degree to which

  2018-11-05

  

  The discount rate is the degree to which a subject reduces the current value of a future reward. Usually, the research measures this rate with choice models by inviting subjects to choose real or hypothetical amounts of money in different time periods (Frederick, Loewenstein, & O’Donoghue, 2002). O

• We thus see that emotion

  2018-11-05

  

  We thus see that emotion regulation depends very much on culture and results in quite different outcomes for the Dutch and Filipino salespeople. These differences stem from the distinct self-concepts (Markus & Kitayama, 1991) and the corresponding distinct display rules (Keltner, Ekman, Gonzaga, & B

• Cell Cycle Compound Library In this study we examined the ro

  2018-11-05

  

  In this study, we examined the role of ADAM17 in colitis by developing dextran sulfate sodium (DSS)-induced colitis using two different conditional Adam17-deficient mice, i.e. mice with systemic deletion by the inducible Mx1-Cre gene of Adam17 (Adam17Mx1-Cre+) or those with its deletion in myeloid C

• Today recent technological advances have dramatically improv

  2018-11-05

  

  Today, recent technological advances have dramatically improved the prospect of applying broadly the concept of precision medicine. Large-scale databases, omics technologies, cellular assays, epigenetics, informatics as well as imaging technologies converge towards optimum disease prevention, diagno

• cycloastragenol Of note is that a minimal improvement both

  2018-11-05

  

  Of note is that a minimal improvement, both in cognitive and neuroanatomical measures, was demonstrated in the OSA patients randomized to BSC over one month (Table 2, Supplementary Table S3). Similar improvement in patients with OSA has been previously associated with the improved sleep quality and

• Androgen signaling is central to prostate cancer

  2018-11-05

  

  Androgen signaling is central to prostate cancer development and progression. A milestone in progression of advanced prostate cancer when it transitions from endocrine-driven to paracrine- or intracrine-driven androgen signaling, with progressive complexities in steroid hormone biosynthesis and alt

• histone acetyltransferase What is the functional significanc

  2018-11-05

  

  What is the functional significance of VPS35/retromer-turning off PTH1R signaling? The increased and sustained PTH(1–34) signaling in Vps35-deficient OB-lineage histone acetyltransferase corroborates well with the impaired PTH(1–34)-driven catabolic response (e.g., RANKL/OPG-expression and OC genes

• Regions of linkage disequilibrium LD were defined for

  2018-11-05

  

  Regions of linkage disequilibrium (LD) were defined for the three loci tagged by SNPs reaching genome-wide significance. rs17599026, associated with urinary frequency, tags a 106kb region of LD (base position 137,657,783–137,763,798; Fig. 2A) containing part of KDM3B (including the promoter region t

• Lung cancer is the most common cancer in US

  2018-11-05

  

  Lung cancer is the most common cancer in US and worldwide (Centers for Disease Control and Prevention and National Center for Health Statistics, 2013; American Cancer Society, 2014), and the survival rate is low (Howlader et al., 2013). Most cases (90%) of lung cancer are attributable to smoking (Ge

• br Conflicts of Interest br Author Contributions J Jian

  2018-11-05

  

  Conflicts of Interest Author Contributions J. Jian designed and performed experiments, collected and analyzed data, and wrote the paper. Q.Y. Tian, S. Zhao, H. Liu, and Y. Zhao performed experiments, collected and analyzed data. W. Chen, and G. Grunig established the chronic lung inflammation

• br In the past thirty years we have seen dramatic

  2018-11-05

  

  In the past thirty years we have seen dramatic advances in vaccine technology and development that have yielded vaccines to protect against the pneumococcus, Hib, rotavirus, HPV, and meningococcal disease amongst others (). We have also seen a paradigm shift in the availability of these vaccines i

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