• Idiopathic pulmonary fibrosis is frequently a

  2018-11-07

  

  Idiopathic pulmonary fibrosis is frequently a fatal condition for which treatment options are limited. Telomeres are shortened and senescence increased in lung fibroblasts from patients with this disease, with increased SASP factor expression in the lungs (Schafer et al., 2017). The SASP appears to

• In addition to Parkinson s

  2018-11-07

  

  In addition to Parkinson\'s disease, abnormal protein voltage gated sodium channel are also observed in several other neurodegenerative disorders, e.g. Alzheimer\'s disease, amyotrophic lateral sclerosis (ALS), polyglutamine diseases, etc., suggesting that common mechanisms underlie these disorders

• Dumas respalda esta posici n al se alar que los

  2018-11-07

  

  Dumas (2010) respalda esta posición al señalar que los países asiáticos mantuvieron una fuerte convicción de modernizar sus economías mediante superávits comerciales, lo que les llevó a acumular una gran cantidad de excedente de recursos que pudieron colocarse posteriormente sobre las economías madu

• br LC MS MS data acquisition br LC MS

  2018-11-07

  

  LC–MS/MS data acquisition LC–MS/MS data analysis, statistical analysis and visualization Data were analyzed and filtered on MaxQuant version 1.2.2 [5] (20ppm error tolerance) with a FDR setting of 1% against the SPROT Yeast database and at a cutoff of at least 2 peptides seen to assign quantit

• In experiments measuring focal adhesion area HUVECs were als

  2018-11-07

  

  In experiments measuring focal adhesion area, HUVECs (4×105) were also settled onto ECM-coated micro-posts as described above. Cells were fixed in 3.7% (w/v) paraformaldehyde in PBS for 10min at R.T. and permeabilized in melanin inhibitor stabilization buffer (100mM, 300mM sucrose, 3mM MgCl2, 1mM E

• fak pathway All statistical analyses were performed using th

  2018-11-07

  

  All statistical analyses were performed using the commercial software Statistical Package for Social Science (SPSS, version 23.0, IL, USA) and NCSS Data version 11.0 (NCSS, LLC). Figures with a p-value Data Here, we provide the expression profile of gene involved in the control of redox homeostasi

• br Experimental design materials and

  2018-11-07

  

  Experimental design, materials and methods Funding sources This work was supported by Paul Sabatier University (Toulouse, France), Région Midi-Pyrénées and by the French Ministry of Higher Education and Research. Acknowledgements Data The dataset contained in this article provides a det

• br Experimental design materials and methods The methodologi

  2018-11-07

  

  Experimental design, materials and methods The methodologies that allowed the data here presented are described in [1] and in cited references. Here, only the protocol for glycosidic RG-108 analysis is provided, giving a large number of experimental details, usually omitted in research articles

• CA074 br Methods In this study a modification of

  2018-11-07

  

  Methods In this study a modification of the original Random Forest algorithm, namely Random forests constructed from conditional trees (Strobl et al., 2009b), is used to classify the households into either LPG or non-LPG users. This section continues with a short description of the Random Forest

• Studies should continue to follow existing adolescent

  2018-11-07

  

  Studies should continue to follow existing adolescent cohorts to understand neural and behavioral changes that occur into young adulthood. Understanding how co-occurring marijuana and alcohol use influences both macrostructural and microstructural proton pump inhibitor development, along with struct

• br Developmental changes in executive systems

  2018-11-07

  

  Developmental changes in executive systems Executive functions (EFs), such as voluntary attention control, intentional response selection, or contextual framing of stimuli, serve to guide behavior, attention, and memory toward or away from predetermined goals. EFs interface with perceptual system

• Neuroimaging studies have demonstrated that a history of

  2018-11-07

  

  Neuroimaging studies have demonstrated that a history of peer rejection and accompanying intra- and interpersonal vulnerability factors are associated with enhanced neural responses to social exclusion in adolescence. Activity in the dorsal Anterior Cingulate Cortex (ACC) – a region involved in dete

• To elucidate the development of neural mechanisms mediating

  2018-11-07

  

  To elucidate the development of neural mechanisms mediating age-related changes in behavior, it lysophospholipid receptor is important to map brain-behavior associations across age (Pfeifer and Allen, 2012). Poldrack has emphasized the importance of quantifying such associations precisely (Poldrack

• The brain should also be expected to

  2018-11-07

  

  The order Embelin should also be expected to underlie differential susceptibility inasmuch as it is intrinsically and reciprocally interconnected with genotypic to phenotypic systems already empirically demonstrated to manifest susceptibility. Activation of the anterior cingulate cortex (ACC), for

• br Discussion The present study investigated the relationshi

  2018-11-07

  

  Discussion The present study investigated the relationship between the 5-HTTLPR polymorphism and neural mechanisms of selective auditory attention in preschool children from lower SES backgrounds. We observed clear differences in a neural index of selective attention as a function of the 5-HTTLPR

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